Bcl-2 Protein

An anti-apoptotic protein that plays a role in the regulation of cell death.

Bcl-xL Protein

An anti-apoptotic protein that is involved in the regulation of cell survival.

Bcl-w Protein

An anti-apoptotic protein that is expressed in a variety of tissues and plays a role in the regulation of cell survival.

Bcl-2 Homology 3 (BH3) Domain

A conserved protein domain that is found in members of the Bcl-2 family and is involved in the regulation of apoptosis.

Bcl-2 Modulator (Bm)

A small molecule that can modulate the activity of Bcl-2 and other members of the Bcl-2 family.

Apoptosis

A type of programmed cell death that occurs in multicellular organisms.